Título: Gene Family-free Genome Comparison
Palestrante: Prof. Jens Stoye, Bielefeld University, Germany.
Data: 13 de maio de 2015, 10h
Local: IME-UFF, Sala de seminários do 4o. andar
Resumo: Many methods in computational comparative genomics require gene family assignments as a prerequisite. While the biological concept of gene families is well established, their computational prediction remains unreliable. This talk will present a new line of research in which family assignments are not presumed. We study several family-free approaches in detecting conserved structures, genome rearrangements and in reconstructing ancestral gene orders. This leads to a number of interesting combinatorial optimization problems, some of which turn out to be surprisingly hard, others are easily polynomial-time solvable.
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